The Axo-Glial Research Group studies the functions of the cells that form ‘myelinated axons’, the nervous system’s ‘wires’. Axons are injured in multiple sclerosis (MS), stroke, Alzheimer’s, motor neuron disease and several other neurodegenerative conditions. We aim to understand why axons are so susceptible and how we might protect them. Our work provided the first functional demonstration that myelinating cells support axonal transport, likely by ‘feeding’ axons, and providing a rationale for research aimed at finding treatments to restore myelin in MS, the most common cause of neurological disability in young adults.

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